Publications
2026
(21) MICROSTRUCTURAL ANALYSIS OF THE HUMAN VENTRICULAR MYOCARDIUM IN SUBJECTS WITH TYPE-II DIABETES
H. Keerthi, S.P. Ramirez, M.Y. Mata Corral, I. Hernandez de Estrada, Z.N. Dorado, C. Gobinath, A.E. Esparza, W. Poon, B. Joddar, "Microstructural analysis of the human ventricular myocardium in subjects with Type-II Diabetes"
Biochemistry and Biophysics Reports, 2026, 45, 102459
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2025
(20) 3D MULTI-TISSUE MICROPHYSIOLOGICAL SYSTEM FOR ANTI-CANCER AND CARDIOTOXICITY DRUG SCREENING WITH AUTOMATED IMAGE ANALYSIS
E.A. Borrego, J.L. Perez, A. Esparza, P. Delgado, K. Moreno, W. Poon, D. Chambers, B. Joddar, S.L. Natividad-Diaz, "3D multi-tissue microphysiological system for anti-cancer and cardiotoxicity drug screening with automated image analysis"
Discover Applied Science, 2025, 7, 853
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(19) A GENERATIVE ARTIFICIAL INTELLIGENCE COPILOT FOR BIOMEDICAL NANOENGINEERING
Y. Wang, H. Song, Y. Teng, G. Huang, J. Qian, H. Wang, S. Dong, J. Ha, Y. Ma, M. Chang, S.D. Jeong, W. Deng, B.R. Schrank, A. Grippin, A. Wu, J.L. Edwards, Y. Zhang, Y. Lin, W. Poon, S. Wilhelm, Y. Bi, L. Teng, Z. Wang, B.Y.S. Kim, W. Jiang, "A generative artificial intelligence copilot for biomedical nanoengineering"
ACS Nano, 2025, 19(20), 19394-19407
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(18) DEVELOPMENT OF CHEMICAL TAGS FOR UNIVERSAL LIPID NANOPARTICLE VISUALIZATION AND TRACKING IN 2D AND 3D IMAGING
H.V. Balcorta, M.Y. Mata Corral, A. Gallegos, J. Chavez, J. Perez, S. Balivada, S.L. Natividad-Diaz, W. Poon, "Development of chemical tags for universal lipid nanoparticle visualization and tracking in 2D and 3D imaging"
Nano Letters, 2025, 25(19), 7682-7689
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2024
(17) SELECTIVE TRANSFECTION OF A TRANSFERRIN RECEPTOR-EXPRESSING CELL LINE WITH DNA-LIPID NANOPARTICLES
I. Vinales*, J.C. Silva-Espinoza*, B.A. Medina, J.E.M. Urbay, M.A. Beltran, D.E. Salinas, M.A. Ramirez-Ramos, R.A. Maldonado, W. Poon, M.L. Penichet, I.C. Almeida, K. Michael, "Selective transfection of a transferrin receptor-expressing cell line with DNA-lipid nanoparticles"
ACS Omega, 2024, 9(38), 39533-39545
* authors contributed equally
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(16) SUPERPARAMAGNETIC NANOPARTICLES COATED WITH NOVEL BIOCOMPATIBLE MATERIALS PRODUCED HIGH SPECIFIC ABSORPTION RATE IN MAGNETIC HYPERTHERMIA
Y. Getahun, A. Habib, V. Erives-Sedano, W.-Y. Lee, W. Poon, A.A. El-Gendy, "Superparamagnetic nanoparticles coated with novel biocompatible materials produced high specific absorption rate in magnetic hyperthermia"
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 693, 134036
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(15) NUCLEIC ACID DELIVERY NANOTECHNOLOGIES FOR IN VIVO CELL PROGRAMMING
H.V. Balcorta*, V. G. Contreras Guerrero*, D. Bisht, W. Poon, “Nucleic acid delivery nanotechnologies for in vivo cell programming”
ACS Applied Bio Materials, 2024, 7(8), 5020-5036
* authors contributed equally
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2023
(14) QUANTIFYING NANOPARTICLE DELIVERY: CHALLENGES, TOOLS, AND ADVANCES
M.Y. Mata Corral*, D.E. Alvarez*, W. Poon, “Quantifying nanoparticle delivery: challenges, tools, and advances”
Current Opinion in Biotechnology, 2023, 85, 103042
* authors contributed equally
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(13) MICROCOMPUTED TOMOGRAPHY FOR THE MICROSTRUCTURE EVALUATION OF 3D BIOPRINTED SCAFFOLDS
S.P. Ramirez*, I. Hernandez*, H.V. Balcorta, P. Kumar, V. Kumar, W. Poon, B. Joddar, “Microcomputed tomography for the microstructure evaluation of 3D bioprinted scaffolds”
ACS Applied Bio Materials, 2024, 7(12), 7799-7808
* authors contributed equally
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2022
(12) IMPACT OF TUMOR BARRIERS ON NANOPARTICLE DELIVERY TO MACROPHAGES
B. Ouyang, B.R. Kingston, W. Poon, Y.-N. Zhang, Z.P. Lin, A.M. Syed, J. Couture-Senécal, W.C.W. Chan, “Impact of tumor barriers on nanoparticle delivery to macrophages”
Molecular Pharmaceutics, 2022, 19(6), 1917-1925
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2021
(11) COMMUNITY-DRIVEN ONLINE INITIATIVES HAVE RESHAPED SCIENTIFIC ENGAGEMENT
J.P.K. Armstrong*, I. de Lázaro*, N.J. Kirkland*, W. Poon*, S. Sindhwani*, “Community-driven online initiatives have reshaped scientific engagement”
Nature Reviews Materials, 2021, 6(11), 963-965
* authors contributed equally
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2020
(10) THE DOSE THRESHOLD FOR NANOPARTICLE TUMOUR DELIVERY
B. Ouyang, W. Poon, Y-N. Zhang, Z.P. Lin, B.R. Kingston, A.J. Tavares, Y. Zhang, J. Chen, M.S. Valic, A.M. Syed, P. MacMillan, J. Couture-Senécal, G. Zheng, W.C.W. Chan, “The dose threshold for nanoparticle tumour delivery”
Nature Materials, 2020, 19(12), 1362-1371
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(9) A FRAMEWORK FOR DESIGNING DELIVERY SYSTEMS
W. Poon*, B.R. Kingston*, B. Ouyang, W. Ngo, W.C.W. Chan, “A framework for designing delivery systems”
Nature Nanotechnology, 2020, 15(10), 819-829
* authors contributed equally
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(8) SUPPRESSING SUBCAPSULAR SINUS MACROPHAGES ENHANCES TRANSPORT OF NANOVACCINES TO LYMPH NODE FOLLICLES FOR ROBUST HUMORAL IMMUNITY
Y-N. Zhang, W. Poon, E. Sefton, W.C.W. Chan, “Suppressing subcapsular sinus macrophages enhances transport of nanovaccines to lymph node follicles for robust humoral immunity”
ACS Nano, 2020, 14(8), 9478-9490
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2019
(7) NANOPARTICLE SIZE INFLUENCES ANTIGEN RETENTION AND PRESENTATION IN LYMPH NODE FOLLICLES FOR HUMORAL IMMUNITY
Y-N. Zhang, J. Lazarovits, W. Poon, B. Ouyang, L.N.M. Nguyen, B.R. Kingston, W.C.W. Chan, “Nanoparticle size influences antigen retention and presentation in lymph node follicles for humoral immunity”
Nano Letters, 2019, 19(510), 7226-7235
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(6) ELIMINATION PATHWAYS OF NANOPARTICLES
W. Poon, Y-N. Zhang, B. Ouyang, B.R. Kingston, J.L.Y. Wu, S. Wilhelm, W.C.W. Chan, “Elimination pathways of nanoparticles”
ACS Nano, 2019, 13(5), 5785-5798
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2017
(5) EFFECT OF REMOVING KUPFFER CELLS ON NANOPARTICLE TUMOR DELIVERY
A.J. Tavares*, Y-N. Zhang*, W. Poon*, Q. Dai, R. Besla, D. Ding, B. Ouyang, A. Li, J. Chen, G. Zheng, C. Robbins, W.C.W. Chan, “Effect of removing Kupffer cells on nanoparticle tumor delivery”
Proceedings of the Natural Academy of Sciences, 2017, 114(51), E10871-10880
* authors contributed equally
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2016
(4) NANOPARTICLE-LIVER INTERACTIONS: CELLULAR UPTAKE AND HEPATOBILIARY ELIMINATION
Y-N. Zhang*, W. Poon*, A.J. Tavares, I.D. McGilvray, W.C.W. Chan, “Nanoparticle-liver interactions: cellular uptake and hepatobiliary elimination”
Journal of Controlled Release, 2016, 240, 332-348
* authors contributed equally
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2015
(3) TARGETING B16 TUMORS IN VIVO WITH PEPTIDE-CONJUGATED GOLD NANOPARTICLES
W. Poon, X. Zhang, D. Bekah, J.G. Teodoro, J.L. Nadeau, “Targeting B16 tumors in vivo with peptide-conjugated gold nanoparticles”
Nanotechnology, 2015, 26(28), 285101
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(2) DETERMINATION OF BIODISTRIBUTION OF ULTRASMALL, NEAR-INFRARED EMITTING GOLD NANOPARTICLES BY PHOTOACOUSTIC AND FLUORESCENCE IMAGING
W. Poon, A. Heinmiller, X. Zhang, J.L. Nadeau, “Determination of biodistribution of ultrasmall, near-infrared emitting gold nanoparticles by photoacoustic and fluorescence imaging”
Journal of Biomedical Optics, 2015, 20(6), 066007
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2014
(1) NANOPARTICLE DRUG FORMULATIONS FOR CANCER DIAGNOSIS AND TREATMENT
W. Poon, X. Zhang, J.L. Nadeau, “Nanoparticle drug formulations for cancer diagnosis and treatment”
Critical Reviews in Oncogenesis, 2014, 19(3-4), 223-245
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